Safe administration of propofol for sedation in children

This study looks at how an anesthetic drug called propofol affects breathing during an endoscopy procedure.

This study will help us to develop a safe rate of administration of propofol for children that will ensure breathing continues normally during sedation procedures. This study will not affect the care of your child but will provide important information about the safe use of propofol in settings where expert anesthesiologists are not available (such as emergency departments or wards).

 This is not an experimental drug or an experimental technique. Propofol is commonly used for procedures like the one your child is scheduled for. All the usual monitoring equipment will be used.

Who can participate in this study?

• In order to participate in the study, your child must be aged 6-15 years, and having an upper or lower gastrointestinal endoscopic  procedure under sedation in the operating room.

Who should not participate in this study?

• Children who have a history or signs of chronic lung disease, an active cold, long term opioid (morphine like drugs) or other sedative drug therapy, or allergy to propofol, eggs, or soybean oil cannot be invited to participate in this study. In addition, children must be in general good health to be involved.  Your child’s anesthesiologist will make this judgment.

Status?

• Data collection completed. Data analysis and publication in progress.