A Pilot Study to Investigate Plasma Bupivacaine Concentrations in Children Receiving Total Intravenous Anaesthesia and Caudal Analgesia
This study will help us to determine if the level of bupivacaine in the blood after caudal epidural varies between children who have received total intravenous anesthesia (TIVA) and children who have received inhalational (gas-based) anaesthesia (IHA).
Who can participate in this study?
- In order to participate in the study, your child must be between 1 and 5 years old, in general good health, and scheduled for elective surgery below the belly button, with planned general and caudal anaesthesia. Your child’s anaesthesiologist will determine if your child is eligible for participation.
Who should not participate in this study?
- Your child should not participate in this study if there is any medical reason she/he should not receive caudal injection, or if she/he has an acute inflammatory process (ongoing or resolved less than 2 weeks prior to the day of her/his surgery). An "inflammatory process" is one in which the body's immune system is activated, usually to fight an infection or in response to an injury to tissues. Common examples of things that can provoke an inflammatory response include a bad cold, chest infection, urinary tract infection, gastroenteritis, breaking a bone, or having surgery.
Status?
- Actively recruting subjects.
For more information, please see the Consent/Information form