The effects of droperidol and ondansetron on dispersion of myocardial repolarization in children

This study looks at how two anti-nausea drugs, called droperidol and ondansetron, affect certain aspects of the heart rhythm in children.Droperidol and ondansetron are not experimental drugs. They have been used for many years to prevent and treat post-operative nausea & vomiting (PONV). We would like to record your child’s heartbeat by taking an ECG (stickers on the chest, arms and legs) before they go to sleep and again after they are asleep. This will not extend the time your child is under anesthetic.

Who can participate in this study?

• In order to participate in the study, your child must be aged 3 - 10 years.

Who should not participate in this study?

• Children with long QT syndrome, a family history of long QT syndrome, or on certain medicines that affect the heartbeat cannot be invited to participate in this study. In addition, children must be in general good health to be involved.  Your child’s anesthesiologist will make this judgment.

Status?

• Data collection completed. Data analysis and publication in progress.

For more information, please see the Consent/Information form